Nutritional Status in Children with End-Stage Kidney Disease Undergoing Hemodialysis and Other Related Factors

Authors

  • Namira Metasyah Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
  • Eka Laksmi Hidayati Department of Child Health, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia

DOI:

https://doi.org/10.58427/apghn.2.3.2023.13-24

Keywords:

nutritional status, children, end-stage kidney disease, hemodialysis

Abstract

Background: Chronic kidney disease causes several changes in the body's function in metabolizing nutrients. This has led to the discovery of cases of malnutrition in chronic kidney disease patients, especially in ESRD patients undergoing hemodialysis. This certainly needs to be a concern because nutrition is very important for children's growth. Therefore, this study was conducted to find out the effect of hemodialysis and other influencing factors on the nutritional status of children.

Methods: The study was conducted with a cross- sectional design by taking secondary data in the form of disease stage, duration of disease, primary etiologic factors, and comorbidities from medical records. Data on the nutritional status of children was obtained by measuring weight and height, and upper arm circumference and then entered into the WHO Anthro application. Demographic data, such as the education level of the father & mother, family economic status, age, and gender were obtained by filling out the Case Report Form (CRF). Twenty respondents met the inclusion and exclusion criteria of this study.

Results: The average nutritional status assessment seen from the body mass index according to age showed results of -2 SD < x < 1 SD with good nutrition interpretation and x <-2 SD (short stature) in terms of height according to age. Based on bivariate analysis, there was no significant effect between duration of hemodialysis, frequency of hemodialysis, etiology, age, sex, and comorbidities (p>0.05) in children with chronic kidney failure who were undergoing hemodialysis on their nutritional status.

Conclusion: The nutritional status of CKD children undergoing hemodialysis was assessed based on body mass index and height according to age. The average results were good nutrition but with short stature. There was no effect of duration, frequency, etiology, age, gender, and comorbidities in children with chronic kidney failure undergoing hemodialysis on their nutritional status.

References

Hidayati EL. Gangguan Ginjal pada Anak. Media Briefing Kenali Gangguan Ginjal pada Anak; Nov 13: Kementrian Kesehatan Republik Indonesia; 2018.

Ariffin NM, Naing L, Pisharam J, Khalil MM, Tamin N, Chong V, et al. Appetite and gastrointestinal symptoms in end stage renal disease patients. J Clin Exp Nephrol. 2016;1(6):0-.https://doi.org/10.21767/2472-5056.100006 DOI: https://doi.org/10.21767/2472-5056.100006

Lazarus JM. Nutrition in hemodialysis patients. American journal of kidney diseases. 1993;21(1):99-105.https://doi.org/10.1016/S0272-6386(12)80731-1 DOI: https://doi.org/10.1016/S0272-6386(12)80731-1

Ikizler TA. Optimal nutrition in hemodialysis patients. Advances in chronic kidney disease. 2013;20(2):181-9.https://doi.org/10.1053/j.ackd.2012.12.002 DOI: https://doi.org/10.1053/j.ackd.2012.12.002

Günes FE. Medical nutrition therapy for hemodialysis patients. Hemodialysis. 2013.https://doi.org/10.5772/53473 DOI: https://doi.org/10.5772/53473

PERNEFRI. Konsensus Dialisis Perhimpunan Nefrologi Indonesia. Jakarta, Indonesia; 2003.

Pardede SO, Chunnaedy S. Penyakit ginjal kronik pada anak. Sari pediatri. 2016;11(3):199-206.https://doi.org/10.14238/sp11.3.2009.199-206 DOI: https://doi.org/10.14238/sp11.3.2009.199-206

Salas P, Pinto V, Rodriguez J, Zambrano MJ, Mericq V. Growth retardation in children with kidney disease. International Journal of Endocrinology. 2013;2013.https://doi.org/10.1155/2013/970946 DOI: https://doi.org/10.1155/2013/970946

Zhang H, Tao Y, Wang Z, Lu J. Evaluation of nutritional status and prognostic impact assessed by the prognostic nutritional index in children with chronic kidney disease. Medicine. 2019;98(34).https://doi.org/10.1097/MD.0000000000016713 DOI: https://doi.org/10.1097/MD.0000000000016713

Group N-KDW. NKF-K/DOQI clinical practice guidelines for anemia of chronic kidney disease. Am J Kidney Dis. 2001;37(1):S182-S238.https://doi.org/10.1016/S0272-6386(01)70008-X DOI: https://doi.org/10.1016/S0272-6386(01)70008-X

Pugh D, Gallacher PJ, Dhaun N. Management of hypertension in chronic kidney disease. Drugs. 2019;79:365-79.https://doi.org/10.1007/s40265-019-1064-1 DOI: https://doi.org/10.1007/s40265-019-1064-1

Ku E, Lee BJ, Wei J, Weir MR. Hypertension in CKD: core curriculum 2019. American Journal of Kidney Diseases. 2019;74(1):120-31.https://doi.org/10.1053/j.ajkd.2018.12.044 DOI: https://doi.org/10.1053/j.ajkd.2018.12.044

Sahathevan S, Khor B-H, Ng H-M, Abdul Gafor AH, Mat Daud ZA, Mafra D, et al. Understanding development of malnutrition in hemodialysis patients: a narrative review. Nutrients. 2020;12(10):3147.https://doi.org/10.3390/nu12103147 DOI: https://doi.org/10.3390/nu12103147

Bramania P, Ruggajo P, Bramania R, Mahmoud M, Furia F. Nutritional status of patients on maintenance hemodialysis at Muhimbili National Hospital in Dar es Salaam, Tanzania: a cross-sectional study. Journal of Nutrition and Metabolism. 2021;2021:1-7.https://doi.org/10.1155/2021/6672185 DOI: https://doi.org/10.1155/2021/6672185

Libowo A, Widiasta A, Rachmadi D. Length of Stay Children Hospitalized with Chronic Kidney Disease Based on Etiology and Stage in Dr. Hasan Sadikin Hospital Bandung. International Journal of Integrated Health Sciences. 2020;8(1):27-31.https://doi.org/10.15850/ijihs.v8n1.1880 DOI: https://doi.org/10.15850/ijihs.v8n1.1880

Kaspar C, Bholah R, Bunchman T. A review of pediatric chronic kidney disease. Blood purification. 2016;41(1-3):211-7.https://doi.org/10.1159/000441737 DOI: https://doi.org/10.1159/000441737

Carrero JJ, Stenvinkel P, Cuppari L, Ikizler TA, Kalantar-Zadeh K, Kaysen G, et al. Etiology of the protein-energy wasting syndrome in chronic kidney disease: a consensus statement from the International Society of Renal Nutrition and Metabolism (ISRNM). Journal of renal nutrition. 2013;23(2):77-90.https://doi.org/10.1053/j.jrn.2013.01.001. DOI: https://doi.org/10.1053/j.jrn.2013.01.001

Erlianda D, Rizal MF. Pertumbuhan dan Perkembangan Anak Penderita Penyakit Ginjal Kronik. Dentika: Dental Journal. 2016;19(1):78-82.https://doi.org/10.32734/dentika.v19i1.157 DOI: https://doi.org/10.32734/dentika.v19i1.157

Ploth DW, Mbwambo JK, Fonner VA, Horowitz B, Zager P, Schrader R, et al. Prevalence of CKD, diabetes, and hypertension in rural Tanzania. Kidney international reports. 2018;3(4):905-15.https://doi.org/10.1016/j.ekir.2018.04.006 DOI: https://doi.org/10.1016/j.ekir.2018.04.006

Nugroho P. Pengelolaan Gangguan Mineral Tulang pada Penyakit Ginjal Kronik. Jurnal Penyakit Dalam Indonesia. 2021;8(4):218-27.https://doi.org/10.7454/jpdi.v8i4.642 DOI: https://doi.org/10.7454/jpdi.v8i4.642

Chan M, Kelly J, Batterham M, Tapsell L. Malnutrition (subjective global assessment) scores and serum albumin levels, but not body mass index values, at initiation of dialysis are independent predictors of mortality: a 10-year clinical cohort study. Journal of Renal Nutrition. 2012;22(6):547-57.https://doi.org/10.1053/j.jrn.2011.11.002 DOI: https://doi.org/10.1053/j.jrn.2011.11.002

Afaghi E, Tayebi A, Sajadi SA, Ebadi A. The relationship between nutritional status based on subjective global assessment and dialysis adequacy. Nephro-Urology Monthly. 2021;13(3).https://doi.org/10.5812/numonthly.116254 DOI: https://doi.org/10.5812/numonthly.116254

Tabibi H, As’ habi A, Heshmati BN, Mahdavi-Mazdeh M, Hedayati M. Prevalence of protein-energy wasting and its various types in Iranian hemodialysis patients: a new classification. Renal failure. 2012;34(10):1200-5.https://doi.org/10.3109/0886022X.2012.718710 DOI: https://doi.org/10.3109/0886022X.2012.718710

Published

2023-08-31

How to Cite

1.
Nutritional Status in Children with End-Stage Kidney Disease Undergoing Hemodialysis and Other Related Factors. Arch Pediatr Gastr Hepatol Nutr [Internet]. 2023 Aug. 31 [cited 2024 Oct. 6];2(3):13-24. Available from: https://apghn.com/index.php/journal/article/view/45